ENERGY SUBSTRATE IS KEY

In the resting state,  BRAIN, HEART, LIVER, and KIDNEYS  consume  the majority of available energy. See: Berg JM, Tymoczko JL, and Stryer L. Biochemistry, 5th ed. New York: WH Freeman, 2002, Section 30.2 “EACH ORGAN HAS A UNIQUE METABOLIC PROFILE: FATTY ACIDS ARE THE HEART’S MAIN SOURCE OF FUEL; ALPHA KETO-ACIDS DERIVED FROM THE DEGRADATION OF AMINO […]

AVOIDING CHRONIC LOW-GRADE METABOLIC ACIDOSIS

Modern Western diets, in general, and ketogenic diets, in particular,  are thought to produce a chronic low-grade metabolic acidosis. Buffering capability may be supported in the following ways: Avoid, when approved by the treating neurologist, anti-convulsant drugs that may interfere with acid/base (pH) homeostasis: valproate (Depakote; Depakene; Epilim; Epival and other brand names);  carbonic anhydrase […]

BETA – OXIDATION

Measures protective of mitochondrial and peroxisomal Beta-Oxidation in High Fat Ketogenic Diets

DAIRY FAT

Practical, Nutritional, and Metabolic Advantages of Butter Oil (Ghee), ~100% Fat Rendered by “Clarifying” Butter

Energy Homeostasis

“Extreme activities are ready, whenever they are needed, to keep uniform the internal environment…. The organism is thrown into convulsions if the sugar supply runs too low, and the convulsions mark the acme of the manoeuvres which bring forth extra sugar from the hepatic reserves to restore the normal glycemic percentage.” Walter Bradford Cannon, and  Claude Bernard […]

NUTRITION, SUPPLEMENTS, and ADDITIVES

ADDITIVES: The Center for Science in the Public Interest published a list of “ten riskiest food additives” that appear to pose the greatest risk to sensitive individuals and the general population. These are acesulfame-K, aspartame, and saccharin, sugar substitutes, artificial colorings, especially Red#3 and yellow #5, BHA and BHT (preservatives), caffeine , MSG, propyl gallate […]