ENERGY SUBSTRATE IS KEY

In the resting state,  BRAIN, HEART, LIVER, and KIDNEYS  consume  the majority of available energy. See: Berg JM, Tymoczko JL, and Stryer L. Biochemistry, 5th ed. New York: WH Freeman, 2002, Section 30.2 “EACH ORGAN HAS A UNIQUE METABOLIC PROFILE: FATTY ACIDS ARE THE HEART’S MAIN SOURCE OF FUEL; ALPHA KETO-ACIDS DERIVED FROM THE DEGRADATION OF AMINO […]

ASEK Diet Protocol

  ASEK diet protocol based on medical ketogenic ratio is available to health care professionals by contacting Dr Alan W.C. Yuen, Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, London, UK.

MODIFIED KETOGENIC DIET BASED ON THE FATTY ACID COMPOSITION OF HUMAN MILK

Ketogenic diet (KD),  a proven treatment for epilepsy, is of interest in mitochondrial and peroxisomal (cellular energy) research. Fat provides up to 90% of calories in KD, yet there is no scientific consensus as to how fatty acids (the constituents of fat) might be exploited to improve efficacy. The composition of fatty acids in cow’s milk closely […]

Energy Homeostasis

“Extreme activities are ready, whenever they are needed, to keep uniform the internal environment…. The organism is thrown into convulsions if the sugar supply runs too low, and the convulsions mark the acme of the manoeuvres which bring forth extra sugar from the hepatic reserves to restore the normal glycemic percentage.” Walter Bradford Cannon, and  Claude Bernard […]

Case History

Poster presented at the 2nd International Symposium on Dietary Therapies for Epilepsy and other Neurological Disorders, Edinburgh, Oct 2010 View pdf:  EdinburghposterFinal Refractory epilepsy controlled by an acidosis sparing, euketonemic ketogenic (ASEK) diet: a case history. A.W.C. Yuen¹, I.A. Walcutt².   Introduction Classical ketogenic diet, the modified Atkins diet and other variants generally produce hyperketonemia (2 – 6 mM/L of […]